Integrative analysis of bulk and single-cell sequencing reveals TNFSF9 as a potential regulator in microsatellite instability stomach adenocarcinoma
These findings provide new insights into the TME of MSI in STAD, emphasizing the significant role of TNFSF9 in shaping MSI-specific TME, enhancing immunotherapy efficacy, and improving patient survival.
Authors
- Xueqing Yao (ORCID: https://orcid.org/0000-0003-0570-7585)
- Jiehui Li (ORCID: https://orcid.org/0000-0002-7812-8878)
- Jiabin Zheng (ORCID: https://orcid.org/0000-0001-7961-4301)
- Jianlong Zhou
- Junjiang Wang (ORCID: https://orcid.org/0000-0003-0097-9346)
- Y. Li (ORCID: https://orcid.org/0000-0002-4854-5523)
- Yucheng Zhang (ORCID: https://orcid.org/0000-0002-7844-3202)
- Yongfeng Liu (ORCID: https://orcid.org/0000-0001-8474-0329)
- Wenxing Zhang (ORCID: https://orcid.org/0000-0003-4313-9136)
- Huolun Feng (ORCID: https://orcid.org/0009-0004-4315-3039)
Institutions
- Ganzhou People's Hospital (CN)
- Guangdong Academy of Medical Sciences (CN)
- Guangdong Provincial People's Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1186/s40001-025-02471-0
- Citations
- 2
- Primary Topic
- Genetic factors in colorectal cancer
- Type
- article
- Field-Weighted Citation Impact
- 2.94