[18F]FDG PET/CT of Langerhans Cell Histiocytosis with Vertebra Plana
We present an <sup>18</sup>F-fluorodeoxyglucose ([<sup>18</sup>F]FDG) positron emission tomography/computed tomography (PET/CT) scan of a 27 y/o patient with long-standing significant B symptoms, diffuse bone pain, increased inflammation parameters, and polydipsia revealing multiple FDG-avid osteolytic lesions of the axial skeleton including a vertebra plana of T7 and paraosseous soft tissue lesions. A CT-guided biopsy confirmed the diagnosis of Langerhans cell histiocytosis (LCH). This case highlights the importance of considering LCH in young patients with vertebral collapse and underscores the role of PET/CT imaging in establishing an accurate diagnosis.
Authors
- Caroline Burgard (ORCID: https://orcid.org/0000-0003-1522-8860)
- Konstantinos Christofyllakis (ORCID: https://orcid.org/0000-0002-0308-388X)
- Samer Ezziddin (ORCID: https://orcid.org/0000-0003-4110-3375)
- Moritz B. Bastian
- Florian Rosar (ORCID: https://orcid.org/0000-0002-2985-4099)
- Tilman Speicher
Institutions
- Saarland University (DE)
Publication Details
- Journal
- Diagnostics
- Published
- 2025-03-28
- DOI
- https://doi.org/10.3390/diagnostics15070862
- Citations
- 1
- Primary Topic
- Histiocytic Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00