Forward Flow in Patients With Heart Failure and Functional Mitral Regurgitation: The COAPT Trial

In the COAPT trial, lower baseline forward flow was associated with worse outcomes in medically managed patients, and those with low baseline forward flow derived the greatest absolute benefit from TEER. However, measured forward flow did not improve with TEER during the 2-year follow-up.

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Publication Details

Journal
Journal of the Society for Cardiovascular Angiography & Interventions
Published
2025-03-28
DOI
https://doi.org/10.1016/j.jscai.2025.102609
Primary Topic
Cardiac Valve Diseases and Treatments
Type
article
Field-Weighted Citation Impact
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article

Forward Flow in Patients With Heart Failure and Functional Mitral Regurgitation: The COAPT Trial

D. Scott Lim, Yanru Li, Zachary M. Gertz, Michael J. Mack et al.
Journal of the Society for Cardiovascular Angiography & Interventions
Cardiac Valve Diseases and Treatments
article

Forward Flow in Patients With Heart Failure and Functional Mitral Regurgitation: The COAPT Trial

D. Scott Lim, Yanru Li, Zachary M. Gertz, Michael J. Mack, Michael Schonning, Björn Redfors, Saibal Kar, Gregg W. Stone, Neil J. Weissman, Federico M. Asch, Zhipeng Zhou, W. Todd Abraham, JoAnn Lindenfeld, Philippe Pibarot
article en

Abstract

In the COAPT trial, lower baseline forward flow was associated with worse outcomes in medically managed patients, and those with low baseline forward flow derived the greatest absolute benefit from TEER. However, measured forward flow did not improve with TEER during the 2-year follow-up.

Journal of the Society for Cardiovascular Angiography & InterventionsVol. 4(5)
Virginia Commonwealth University (US), Cornell University (US), Bakersfield Heart Hospital (US), Sahlgrenska University Hospital (SE), St. Francis Hospital (US), Lung Institute (US), Baylor Medical Center at Garland (US), Heart Hospital Baylor Plano (US), Los Robles Hospital & Medical Center (US), Cardiovascular Research Foundation (US), Vanderbilt Health (US), Université Laval (CA), Weill Cornell Medicine (US), University of Virginia (US), The Ohio State University (US), MedStar Health (US), University of Gothenburg (SE), Icahn School of Medicine at Mount Sinai (US), Core Laboratories (United States) (US)
Openalex Percentile: Top 91%
Cardiac Valve Diseases and Treatments
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