Effect of miR-654-3p targeting EMP1 on osteoblast activity and differentiation in delayed fracture healing
miR-654-3p and EMP1 are aberrantly expressed in DFH, and both have high diagnostic value for DFH. miR-654-3p is involved in the proliferation, differentiation, and apoptotic activities of osteoblasts by regulating the level of EMP1, thus affecting the progression of DFH.
Authors
- Danzhi Li
- Shengliang Sun
- Shantao Wang
- Mingwei Wang (ORCID: https://orcid.org/0000-0001-9060-5107)
- Xinsheng Liu (ORCID: https://orcid.org/0000-0001-7609-796X)
Institutions
- Yidu Central Hospital of Weifang (CN)
Publication Details
- Journal
- Journal of Orthopaedic Surgery and Research
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1186/s13018-025-05736-w
- Citations
- 5
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 4.03