Hormonal and metabolic influences on outcomes in PCOS undergoing assisted reproduction: the role of BMI in fresh embryo transfers

Hormonal imbalances and glucose-lipid metabolism have minimal influence on embryo development in PCOS patients. However, hormonal factors-particularly in PCOS patients with high BMI-significantly influence pregnancy outcomes, with elevated BMI and androgen levels increasing the risk of miscarriage. These findings underscore the importance of addressing metabolic and hormonal factors in the management of PCOS patients undergoing ART.

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Publication Details

Journal
BMC Pregnancy and Childbirth
Published
2025-03-28
DOI
https://doi.org/10.1186/s12884-025-07480-9
Citations
9
Primary Topic
Ovarian function and disorders
Type
article
Field-Weighted Citation Impact
15.28
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article

Hormonal and metabolic influences on outcomes in PCOS undergoing assisted reproduction: the role of BMI in fresh embryo transfers

Xihong Zhou, Mei Leng, Jiuzhi Zeng, Dongsheng Xiong et al.
9 citations
BMC Pregnancy and Childbirth
Ovarian function and disorders
15.28
article

Hormonal and metabolic influences on outcomes in PCOS undergoing assisted reproduction: the role of BMI in fresh embryo transfers

Xihong Zhou, Mei Leng, Jiuzhi Zeng, Dongsheng Xiong, Li Wang, Rong Li, Weixin Liu, Xiaoyu Yu, Libing He, Heqiu Yan, Mei Liang, Erniu Jike
article en
9 citations

Abstract

Hormonal imbalances and glucose-lipid metabolism have minimal influence on embryo development in PCOS patients. However, hormonal factors-particularly in PCOS patients with high BMI-significantly influence pregnancy outcomes, with elevated BMI and androgen levels increasing the risk of miscarriage. These findings underscore the importance of addressing metabolic and hormonal factors in the management of PCOS patients undergoing ART.

BMC Pregnancy and ChildbirthVol. 25(1)
Chengdu Medical College (CN), Chengdu Women's and Children's Central Hospital (CN)
Openalex Percentile: Top 1%
Ovarian function and disorders
15.28
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