Thrombospondin-1 Airway Expression and Thrombospondin-1 Gene Variants Are Associated with Bronchopulmonary Dysplasia in Extremely Low-Birth-Weight Infants: A Pilot Study
Although no individual variants differed, two THBS1 haplotypes and early TSP-1 airway expression varied by BPD severity, suggesting a role for TSP-1 in lung development and BPD pathogenesis in ELBW infants.
Authors
- Lance A. Parton (ORCID: https://orcid.org/0000-0002-7015-3200)
- Hannah J. Sampath (ORCID: https://orcid.org/0009-0009-1847-5446)
- Parvathy Krishnan (ORCID: https://orcid.org/0009-0005-7278-0565)
- Van Trinh
Institutions
- Tufts Medical Center (US)
- Westchester Medical Center (US)
- New York Medical College (US)
- Detroit Medical Center (US)
- Maria Fareri Children's Hospital (US)
- Hutzel Women's Hospital (US)
- Children's Hospital of Michigan (US)
Publication Details
- Journal
- Children
- Published
- 2025-03-28
- DOI
- https://doi.org/10.3390/children12040424
- Primary Topic
- Neonatal Respiratory Health Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00