Factors that predict progression of von Hippel-Lindau disease-related malignancy: a longitudinal cohort study
Genetic subtype was not associated with progression of vHL disease, but missense mutations were associated with higher treatment rates for RCC and adrenal pheochromocytoma. The finding that progression of Hb and RCC is linked to larger baseline tumor volume and male sex may facilitate clinical management.
Authors
- Moinay Kim (ORCID: https://orcid.org/0000-0002-6443-7098)
- Joo‐Yong Lee (ORCID: https://orcid.org/0000-0003-1049-6006)
- Dae Wook Hwang (ORCID: https://orcid.org/0000-0002-1749-038X)
- Beom Hee Lee (ORCID: https://orcid.org/0000-0001-9709-2631)
- Cheryn Song (ORCID: https://orcid.org/0000-0002-1823-4281)
- Hyun Young Lee (ORCID: https://orcid.org/0000-0003-4169-8284)
- Sangjoon Chong (ORCID: https://orcid.org/0000-0003-4361-8401)
- Jae Ho Lee (ORCID: https://orcid.org/0000-0002-5810-4852)
- Minju Kim (ORCID: https://orcid.org/0000-0001-7188-9204)
- Ji Eun Park
Institutions
- Ulsan College (KR)
- Soonchunhyang University Hospital Seoul (KR)
- Asan Medical Center (KR)
- Samsung Medical Center (KR)
- University of Ulsan (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1186/s12885-025-13985-5
- Primary Topic
- Cancer, Hypoxia, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00