Intra-articular administration of autologous adipose-derived stem cells in hip osteoarthritis: Longitudinal treatment trajectories and prognostic factors
Intra-articular ASC treatment enhanced patient-reported outcomes over 6 months, with differences observed across hip OA severities. Female sex and moderate hip OA were positive prognostic factors, whereas ligamentum teres abnormalities were negative prognostic factors for patient-reported outcomes after ASC treatment. These findings can be used to inform patients and clinicians about the expected course of treatment and aid clinical decision-making regarding the use of intra-articular ASC treatment for hip OA.
Authors
- Shuichi Yoshida
- Taku Saito (ORCID: https://orcid.org/0000-0003-4911-3930)
- Ryota Yamagami (ORCID: https://orcid.org/0000-0002-9150-4911)
- Tomohiro Terao
- Hisatoshi Ishikura (ORCID: https://orcid.org/0000-0001-6317-6087)
- Yuji Maenohara (ORCID: https://orcid.org/0000-0001-7212-0237)
- Shinsaku Tsuji
- Sakae Tanaka (ORCID: https://orcid.org/0000-0001-9210-9414)
- Junya Higuchi
- Masaki Hatano (ORCID: https://orcid.org/0000-0002-7096-5604)
- Yusuke Arino
- Taro Kasai (ORCID: https://orcid.org/0000-0002-5523-1602)
- Yuma Makii
- Tokio Matsuzaki (ORCID: https://orcid.org/0000-0003-1188-5003)
- Ryo Murakami (ORCID: https://orcid.org/0000-0002-1504-2989)
- Masashi Sato
- Keita Inoue
Institutions
- Ochanomizu University (JP)
- SMC Corporation (Japan) (JP)
- GC Corporation (Japan) (JP)
- Chiba Rosai Hospital (JP)
- The University of Tokyo (JP)
Publication Details
- Journal
- Regenerative Therapy
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1016/j.reth.2025.03.010
- Citations
- 1
- Primary Topic
- Osteoarthritis Treatment and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 1.67