The impact of childhood maltreatment, HIV status, and their interaction on mental health outcomes and markers of systemic inflammation in women
Our findings highlight the impact of childhood maltreatment on depression and PTSD symptoms and LPS concentrations in women. These results underscore the importance of trauma-informed health care in addressing childhood maltreatment to potentially improve both mental and physical health outcomes of adult women.
Authors
- Brahmchetna Bedi (ORCID: https://orcid.org/0000-0003-0504-1277)
- A.R. Powers
- Gretchen N. Neigh (ORCID: https://orcid.org/0000-0003-0955-9161)
- Amanda R. Arnold
- Cecile Delille Lahiri (ORCID: https://orcid.org/0000-0002-5605-8266)
- C. Christina Mehta (ORCID: https://orcid.org/0000-0001-6854-7983)
- Heqiong Wang
- Caitlin A. Moran (ORCID: https://orcid.org/0000-0001-8436-0465)
- Jessica A. Alvarez (ORCID: https://orcid.org/0000-0002-7612-1162)
- Knut Hagen (ORCID: https://orcid.org/0000-0003-2111-8895)
- Arshed A. Quyyumi
- Christine R. Kirkpatrick (ORCID: https://orcid.org/0000-0002-4451-8042)
- Paula-Dene C. Nesbeth (ORCID: https://orcid.org/0000-0001-6186-6068)
- M. Neale Weitzmann (ORCID: https://orcid.org/0000-0003-3305-5748)
- Ighovwerha Ofotokun (ORCID: https://orcid.org/0000-0003-2735-1903)
- Vasiliki Michopoulos (ORCID: https://orcid.org/0000-0003-2531-923X)
- Alicia K. Smith (ORCID: https://orcid.org/0000-0002-8537-5156)
Institutions
- Emory Healthcare (US)
- Emory University (US)
- Virginia Commonwealth University (US)
- Veterans Health Administration (US)
Publication Details
- Journal
- Biology of Sex Differences
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1186/s13293-025-00704-9
- Primary Topic
- Child Abuse and Trauma
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institute on Aging
- National Heart, Lung, and Blood Institute