Inflammation and macrophage polarization are associated with Modic change type in lumbar radiculopathy
This study elucidates a close association of MC type I and M1 macrophage. MC type II were observed more often in patients with larger HNPs. This is indicative for MC typing as an important factor in prediction modelling and it suggests the potential for personalized treatment strategies.
Authors
- Wensen Li (ORCID: https://orcid.org/0000-0002-6261-2278)
- Carmen Vleggeert‐Lankamp (ORCID: https://orcid.org/0000-0001-9597-7225)
- Niek Djuric (ORCID: https://orcid.org/0000-0002-5556-6955)
- Christiaan Mink
Institutions
- Medisch Centrum Haaglanden (NL)
- Spaarne Ziekenhuis (NL)
Publication Details
- Journal
- Brain and Spine
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1016/j.bas.2025.104249
- Citations
- 1
- Primary Topic
- Spine and Intervertebral Disc Pathology
- Type
- article
- Field-Weighted Citation Impact
- 1.47