Synergistic potential of CDH3 in targeting CRC metastasis and enhancing immunotherapy
This study provides novel insights into CDH3's role in CRC metastasis and its potential as a therapeutic target. The translational potential of CDH3, including its integration with immunotherapy and drug repositioning strategies, offers a promising avenue for the treatment of metastatic CRC.
Authors
- Zhaojin Yu (ORCID: https://orcid.org/0000-0002-0438-5601)
- Jia Fu
- Chen Fu (ORCID: https://orcid.org/0000-0002-2343-1802)
- Chaoyue Liu (ORCID: https://orcid.org/0000-0002-4230-9159)
Institutions
- China Medical University (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1186/s12885-025-13845-2
- Citations
- 4
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 3.22
Funders
- National Natural Science Foundation of China