Rabbit Models for Infectious Diseases Caused by Staphylococcus aureus

Staphylococcus aureus (S. aureus) is a disreputable symbiotic bacterium that is responsible for a range of diseases, including life-threatening pneumonia, endocarditis, septicemia, and others, which has led to an immense loss in both public health and economy, imposing a significant burden on society. To investigate the pathogenic mechanism of S. aureus and develop new treatment methods for infectious diseases caused by S. aureus, various rabbit models have been developed to simulate different infections by S. aureus, such as pneumonia models, meningitis models, and endocarditis models, etc. In this review, we summarized the application of rabbit models in S. aureus-induced infectious diseases.