Impact of splenectomy on prognosis in lymphoma with splenic involvement
In this group of lymphoma patients presenting with splenic invasion as the first manifestation, the pathological type was almost aggressive lymphoma, with DLBCL being the main subtype. Common clinical symptoms include elevated ferritin, prolonged APTT and high LDH levels. This study suggests that splenectomy should be considered for these patients when their overall condition allows for safe intervention. Splenectomy combined with chemotherapy can significantly improve the survival time of patients.
Authors
- Mengqi Xiong
- Jingsong He (ORCID: https://orcid.org/0000-0002-1190-1037)
- Lixia Zhu (ORCID: https://orcid.org/0000-0002-8762-278X)
- Xiujin Ye (ORCID: https://orcid.org/0000-0002-4553-2751)
- Li Li (ORCID: https://orcid.org/0000-0003-2247-5720)
- Lulu Wang (ORCID: https://orcid.org/0000-0002-8838-6467)
- Kui Zhao (ORCID: https://orcid.org/0000-0001-9338-6675)
- Lijun Wang
Institutions
- Zhejiang University (CN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1186/s40001-025-02465-y
- Primary Topic
- Lymphoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Zhejiang Province