Mo-Mediated Reductive Cyclization/Allylation of 2-Alkynyl Nitroarenes with 1,3-Dienes: Synthesis of 3-Allylindoles
3-Allylindoles constitute a key structural feature in many natural products and bioactive compounds. In this work, we developed a Mo-mediated reductive cyclization/allylation of 2-alkynyl nitroarenes with 1,3-dienes. Using Mo(CO)<sub>6</sub> as both the reductant and the catalyst, a broad range of functionalized 3-allylindoles were prepared in good to excellent yields from easily available 2-alkynylnitroarenes and 1,3-dienes as starting materials.
Authors
- Yong-Yu He
- Jin‐Bao Peng (ORCID: https://orcid.org/0000-0002-0568-7740)
- Yi Liu (ORCID: https://orcid.org/0000-0002-3954-6102)
- Hongguang Li (ORCID: https://orcid.org/0000-0002-6579-7300)
- Jia-Yi Feng
- Jian-Bang Hu
Institutions
- Wuyi University (CN)
Publication Details
- Journal
- Organic Letters
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1021/acs.orglett.5c00624
- Citations
- 1
- Primary Topic
- Nanomaterials for catalytic reactions
- Type
- article
- Field-Weighted Citation Impact
- 0.94
Funders
- Wuyi University
- Department of Education of Guangdong Province