Evaluation of real-world use of pulmonary embolism thrombolysis: ERUPT

PE thrombolysis in the UK deviates from international guidelines in a significant minority of cases; comprising the use of reduced-dose regimens and thrombolysis in non-high-risk cases without haemodynamic deterioration. Prospective real-world studies, assessing clinical practice and outcomes following thrombolysis, should be conducted to understand the pragmatic application of evidence and inform future guidelines.

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Publication Details

Journal
ERJ Open Research
Published
2025-03-28
DOI
https://doi.org/10.1183/23120541.00935-2024
Primary Topic
Venous Thromboembolism Diagnosis and Management
Type
article
Field-Weighted Citation Impact
0.00

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article

Evaluation of real-world use of pulmonary embolism thrombolysis: ERUPT

Ross Thompson, Kay‐Pong Yip, Cecillia Rafique, Ruth Sobala et al.
ERJ Open Research
Venous Thromboembolism Diagnosis and Management
article

Evaluation of real-world use of pulmonary embolism thrombolysis: ERUPT

Ross Thompson, Kay‐Pong Yip, Cecillia Rafique, Ruth Sobala, Romit Samanta, Najib Mahboob Rahman, Joseph Kibbler, Anthony De Soyza, Akhilesh Jha, Matthew Steward
article en

Abstract

PE thrombolysis in the UK deviates from international guidelines in a significant minority of cases; comprising the use of reduced-dose regimens and thrombolysis in non-high-risk cases without haemodynamic deterioration. Prospective real-world studies, assessing clinical practice and outcomes following thrombolysis, should be conducted to understand the pragmatic application of evidence and inform future guidelines.

ERJ Open ResearchVol. 11(3)
University of Cambridge (GB), Royal Devon & Exeter NHS Foundation Trust (GB), Northumbria Healthcare NHS Foundation Trust (GB), Churchill Hospital (GB), Newcastle upon Tyne Hospitals NHS Foundation Trust (GB), Freeman Hospital (GB), Northern Devon Healthcare NHS Trust (GB), South Tyneside and Sunderland NHS Foundation Trust (GB), University of Birmingham (GB), Newcastle University (GB)
Asthma and Lung UK
Openalex Percentile: Top 87%
Venous Thromboembolism Diagnosis and Management
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