Leukemia Inhibitory Factor Attenuates Hypoxic–Ischemic White Matter Injury via NLRP3 Inflammasome Activity Suppressing Through the Nrf2/HO-1 Pathway
NLRP3-dependent pyroptosis plays a role in PWMI pathogenesis; moreover, LIF mitigates OGD/R-induced pyroptosis-dependent neurotoxicity by upregulating HO-1 expression in rat astrocytes.
Authors
- Hua Wang
- Liang Huo (ORCID: https://orcid.org/0000-0002-6711-2950)
- Xueyan Liu (ORCID: https://orcid.org/0009-0005-6419-5809)
Institutions
- China Medical University (CN)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-03-19
- DOI
- https://doi.org/10.31083/fbl36630
- Citations
- 1
- Primary Topic
- Inflammasome and immune disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.81