Novel Plasma Biomarkers for Alzheimer’s Disease: Insights from Organotypic Brain Slice and Microcontact Printing Techniques
Here we show that brain slices connected to human plasma prints allow the identification of novel human AD biomarkers with subsequent mass spectrometry. This technique represents a novel and innovative approach to translate research findings from mouse models to human applications.
Authors
- Josef Marksteiner
- Bettina Sarg (ORCID: https://orcid.org/0000-0002-4785-8739)
- Necat Yılmaz (ORCID: https://orcid.org/0000-0003-1759-3052)
- Christian Humpel (ORCID: https://orcid.org/0000-0001-7641-4240)
- Katharina Steiner (ORCID: https://orcid.org/0009-0003-2449-4885)
- Klaus Faserl (ORCID: https://orcid.org/0000-0003-1646-3256)
Institutions
- Innsbruck Medical University (AT)
- Universität Innsbruck (AT)
- Tirol Kliniken (AT)
- Mersin Üniversitesi (TR)
Publication Details
- Journal
- Frontiers in Bioscience-Landmark
- Published
- 2025-03-24
- DOI
- https://doi.org/10.31083/fbl36257
- Citations
- 1
- Primary Topic
- Barrier Structure and Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.84