Association of circulating metabolic biomarkers with risk of lung cancer: a population-based prospective cohort study
Glycoprotein acetyls had a positive association with lung cancer risk while other metabolites and lipoprotein subfractions showed negative associations. Certain metabolites and lipoprotein subfractions might be independent risk factors for lung cancer. Our findings shed new light on the etiology of lung cancer and might aid the selection of high-risk individuals for lung cancer screening.
Authors
- Jiahao Lin
- Lan Wu (ORCID: https://orcid.org/0000-0001-8286-1063)
- Mengmeng Li (ORCID: https://orcid.org/0000-0001-6630-7468)
- Jun Yang
- Yu Chen (ORCID: https://orcid.org/0000-0001-9767-4797)
- Wenkai Huang
Institutions
- Sun Yat-sen University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Sun Yat-sen University Cancer Center (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- BMC Medicine
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1186/s12916-025-03993-4
- Citations
- 1
- Primary Topic
- Cancer, Lipids, and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.94