Genicular Nerve Ultrasound-Guided Cryoanalgesia for the Treatment of Chronic Knee Joint Pain: An Observational Retrospective Study
Ultrasound-guided GNCryo is a promising minimally invasive treatment for chronic knee pain, providing pain relief and improved quality of life for up to 9 months. Although some outcomes showed a trend toward baseline over time, pain relief remained lower than baseline, consistent with potential nerve regeneration or recovery. Larger prospective, controlled trials are necessary to confirm these findings and to refine patient selection and technique optimization.
Authors
- Christopher L Robinson
- R. Jason Yong (ORCID: https://orcid.org/0000-0001-6960-9621)
- Giuliano Lo Bianco (ORCID: https://orcid.org/0000-0003-2705-1548)
- Guilherme Henrique Souza dos Santos
- Agnes Reka Stogicza (ORCID: https://orcid.org/0000-0001-8045-9185)
- Andrea M. Trescot (ORCID: https://orcid.org/0000-0001-8456-6340)
- Matteo Luigi Giuseppe Leoni (ORCID: https://orcid.org/0000-0001-5228-3733)
- Francesco D’Angelo (ORCID: https://orcid.org/0000-0003-3606-4228)
Institutions
- Brigham and Women's Hospital (US)
- University of Szeged (HU)
- Hospital Clínic de Barcelona (ES)
- Fondazione Istituto G. Giglio di Cefalù (IT)
- Center for Neuroscience and Regenerative Medicine (US)
- Azienda Ospedaliera Universitaria Policlinico "Paolo Giaccone" di Palermo (IT)
- Universitat de Barcelona (ES)
- Sapienza University of Rome (IT)
Publication Details
- Journal
- Pain and Therapy
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1007/s40122-025-00727-5
- Citations
- 4
- Primary Topic
- Orthopedic Surgery and Rehabilitation
- Type
- article
- Field-Weighted Citation Impact
- 8.03