A rare case of multiple myeloma with double translocations: t(11;14) and t(14;16)

Multiple myeloma is a clonal plasma cell malignancy often characterized by complex cytogenetic abnormalities that influence prognosis and treatment strategies. This report describes a 63-year-old male with kappa light chain multiple myeloma and a rare finding of double translocation involving t(11;14) and t(14;16), detected by FISH analysis. This case emphasizes the clinical implications of such genetic abnormalities and their impact on disease progression and therapeutic decisions.

Authors

Institutions

Publication Details

Journal
Journal of Hematopathology
Published
2025-03-27
DOI
https://doi.org/10.1007/s12308-025-00626-w
Primary Topic
Multiple Myeloma Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

A rare case of multiple myeloma with double translocations: t(11;14) and t(14;16)

David Glen Coffey, Mina Meseha, Ping Yang, Vishw Patel et al.
Journal of Hematopathology
Multiple Myeloma Research and Treatments
article

A rare case of multiple myeloma with double translocations: t(11;14) and t(14;16)

David Glen Coffey, Mina Meseha, Ping Yang, Vishw Patel, Kirolos Sekla
article en

Abstract

Multiple myeloma is a clonal plasma cell malignancy often characterized by complex cytogenetic abnormalities that influence prognosis and treatment strategies. This report describes a 63-year-old male with kappa light chain multiple myeloma and a rare finding of double translocation involving t(11;14) and t(14;16), detected by FISH analysis. This case emphasizes the clinical implications of such genetic abnormalities and their impact on disease progression and therapeutic decisions.

Journal of HematopathologyVol. 18(1)
Cleveland Clinic (US), University of Miami (US), Alexandria University (EG)
Good health and well-being
Openalex Percentile: Top 92%
Multiple Myeloma Research and Treatments
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

A rare case of multiple myeloma with double translocations: t(11;14) and t(14;16) — David Glen Coffey, Mina Meseha, et al. · Journal of Hematopathology (2025) | TGRS Research Map | TGRS