Aggressive subtypes in basal cell carcinomas might need different treatment and follow-up due to the higher risk of surgically uncontrollable recurrences

Our results show the impact of incomplete tumor resection and aggressive subtype on patient outcome after BCC surgery. We suggest that the aggressiveness of the BCC may be the precondition for multiple recurring BCCs. Furthermore, especially patients who underwent surgery outside our Departments showed R1 situations and rBCCs. Therefore, personalized treatment and follow-up care as well as efforts to avoid high-risk recurrences with aggressive subtypes are necessary to improve long-term success after surgery and should be conducted by a specialized center.

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Publication Details

Journal
Graefe s Archive for Clinical and Experimental Ophthalmology
Published
2025-03-26
DOI
https://doi.org/10.1007/s00417-025-06807-8
Primary Topic
Nonmelanoma Skin Cancer Studies
Type
article
Field-Weighted Citation Impact
0.00

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article

Aggressive subtypes in basal cell carcinomas might need different treatment and follow-up due to the higher risk of surgically uncontrollable recurrences

Robert E. Beach, Stefanie Gniesmer, Sara H. Yang, Vinodh Kakkassery et al.
Graefe s Archive for Clinical and Experimental Ophthalmology
Nonmelanoma Skin Cancer Studies
article

Aggressive subtypes in basal cell carcinomas might need different treatment and follow-up due to the higher risk of surgically uncontrollable recurrences

Robert E. Beach, Stefanie Gniesmer, Sara H. Yang, Vinodh Kakkassery, Joyce Tohme, Svenja Rebecca Sonntag, Armin Mohi, Salvatore Grisanti
article en

Abstract

Our results show the impact of incomplete tumor resection and aggressive subtype on patient outcome after BCC surgery. We suggest that the aggressiveness of the BCC may be the precondition for multiple recurring BCCs. Furthermore, especially patients who underwent surgery outside our Departments showed R1 situations and rBCCs. Therefore, personalized treatment and follow-up care as well as efforts to avoid high-risk recurrences with aggressive subtypes are necessary to improve long-term success after surgery and should be conducted by a specialized center.

Graefe s Archive for Clinical and Experimental OphthalmologyVol. 263(7)
Klinikum Chemnitz (DE), University of Lübeck (DE)
Universität zu Lübeck
Good health and well-being
Openalex Percentile: Top 91%
Nonmelanoma Skin Cancer Studies
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Aggressive subtypes in basal cell carcinomas might need different treatment and follow-up due to the higher risk of surgically uncontrollable recurrences — Robert E. Beach, Stefanie Gniesmer, et al. · Graefe s Archive for Clinical and Experimental Ophthalmology (2025) | TGRS Research Map | TGRS