Cognitive and Adaptive Functioning of CTNNB1 Syndrome Patients: A Comparison With Autism Spectrum Disorder and Cerebral Palsy
This is the first study to compare the cognitive and adaptive functioning of CTNNB1 syndrome patients with control diseases and detect significant difference. Although intellectual disability is one of the main manifestations of the CTNNB1 syndrome, patients performed better on verbal cognitive tasks than in visuospatial and logical thinking exercises, while adaptive functioning performances did not differ from control groups.
Authors
- Caroline E. Nunes‐Xavier (ORCID: https://orcid.org/0000-0002-1875-6645)
- Mercè Pallarès‐Sastre (ORCID: https://orcid.org/0009-0000-2386-3595)
- Imanol Amayra (ORCID: https://orcid.org/0000-0002-3250-628X)
- Sonia Bañuelos (ORCID: https://orcid.org/0000-0002-1399-381X)
- Rafael Pulido (ORCID: https://orcid.org/0000-0001-9100-248X)
- Fabio Cavaliere (ORCID: https://orcid.org/0000-0003-2003-522X)
- Maitane García (ORCID: https://orcid.org/0000-0003-0895-1751)
Institutions
- Ikerbasque (ES)
- Oslo University Hospital (NO)
- Universidad de Deusto (ES)
- University of the Basque Country (ES)
- BioCruces Health research Institute (ES)
- Achucarro Basque Center for Neuroscience (ES)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- Instituto Biofisika (ES)
Publication Details
- Journal
- Journal of Intellectual Disability Research
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1111/jir.13235
- Citations
- 2
- Primary Topic
- Congenital heart defects research
- Type
- article
- Field-Weighted Citation Impact
- 1.61
Funders
- Fundación Inocente, Inocente
- Federación Española de Enfermedades Raras