Fecal Secretory Immunoglobulin A and Lactate Level as a Biomarker of Mucosal Immune Dysfunction in Horses With Colic
This study demonstrates the feasibility of using fecal samples to identify biomarkers of colic in horses. An increase in fecal SIgA in horses with colic might suggest the presence of inflammation within the intestines and disruption of the mucosal barrier. These data highlight changes in gastrointestinal barrier and immune function and the intestinal microbiota's metabolic activity in horses with colic.
Authors
- Anna Chełmońska‐Soyta (ORCID: https://orcid.org/0000-0001-7360-3257)
- Agnieszka Żak (ORCID: https://orcid.org/0000-0002-3532-6508)
- Joanna Bajzert (ORCID: https://orcid.org/0000-0002-1299-7405)
- Natalia Siwińska (ORCID: https://orcid.org/0000-0002-5205-5826)
- Zuzana Drábková
- Vaiva Sergedaite
- Dominika Pasak
Institutions
- University of Veterinary Sciences Brno (CZ)
- Wrocław University of Environmental and Life Sciences (PL)
- University of Veterinary Science (MM)
Publication Details
- Journal
- Journal of Veterinary Internal Medicine
- Published
- 2025-03-29
- DOI
- https://doi.org/10.1111/jvim.70073
- Primary Topic
- Veterinary Equine Medical Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00