Determining the Usefulness of Selected Laboratory Markers of Inflammation in Qualifying Patients for <scp>T2</scp> Biosystems Determination
A single analysis of parameters such as C-reactive protein (CRP), white blood cells (WBC), #neutr, #lymph, and neutrophil-to-lymphocyte ratio (NLR) is not a good indicator that could be used as an additional tool facilitating patient qualification for T2Dx testing. The most sensitive parameter distinguishing between patients with a positive T2Dx result and those with a negative result is the measurement of IL-6 and PCT. Proper patient qualification for T2Dx testing can significantly contribute to reducing the time to initiate targeted antibiotic therapy and may impact reducing mortality and improving long-term treatment outcomes.
Authors
- Małgorzata M. Skiba (ORCID: https://orcid.org/0000-0001-9637-9016)
- Mateusz Szymański (ORCID: https://orcid.org/0000-0003-4366-3165)
- Małgorzata Piasecka (ORCID: https://orcid.org/0009-0009-6432-2571)
Institutions
- Medical University of Lublin (PL)
- Cardinal Stefan Wyszynski University in Warsaw (PL)
Publication Details
- Journal
- Journal of Clinical Laboratory Analysis
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1002/jcla.70021
- Primary Topic
- Sepsis Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00