Eligibility Criteria in Advanced Urothelial Cancer Clinical Trials: An Assessment of Modernization and Inclusion
HIV infection and hepatitis B/C infection were commonly identified in exclusion criteria across these trials despite limited evidence suggesting these criteria significantly impact therapy efficacy and tolerability. Broadening and modernization of eligibility criteria will ensure more inclusive clinical trials.
Authors
- Adam Rock (ORCID: https://orcid.org/0000-0002-5859-6965)
- Zeynep Büşra Zengin (ORCID: https://orcid.org/0000-0002-2751-5915)
- Anna O'Dell
- Kyle O. Lee (ORCID: https://orcid.org/0000-0002-9361-3804)
- Benjamin Mercier (ORCID: https://orcid.org/0000-0002-8026-9514)
- Sweta R. Prajapati
- Matthew I. Feng
- Sumanta Kumar Pal (ORCID: https://orcid.org/0000-0002-1712-0848)
- Alex Chehrazi‐Raffle (ORCID: https://orcid.org/0000-0001-5205-4527)
- Jalen Patel
- Errol J. Philip (ORCID: https://orcid.org/0000-0002-1320-6708)
- Ameish Govindarajan (ORCID: https://orcid.org/0000-0002-8113-8524)
- Sandy Liu (ORCID: https://orcid.org/0000-0001-8478-4540)
- Luís Meza (ORCID: https://orcid.org/0000-0002-0235-297X)
- Ishaan Sehgal
- Daniela V. Castro (ORCID: https://orcid.org/0000-0002-5423-9821)
- Elyse H. Chan
- Hedyeh Ebrahimi (ORCID: https://orcid.org/0000-0003-3647-7356)
- Abhishek Tripathi (ORCID: https://orcid.org/0000-0002-5198-0673)
- Joann Hsu (ORCID: https://orcid.org/0000-0001-9452-5980)
- Nazlı Dizman (ORCID: https://orcid.org/0000-0002-3907-8513)
- Tanya Barauskas Dorff (ORCID: https://orcid.org/0000-0001-5990-298X)
- Xiaochen Li (ORCID: https://orcid.org/0000-0002-2161-6168)
Institutions
- City Of Hope National Medical Center (US)
- City of Hope (US)
Publication Details
- Journal
- Cancer Medicine
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1002/cam4.70696
- Citations
- 2
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.01