The problem of recurrence of ovarian endometriomas

Objective : this article is a scientific review of the literature devoted to the important problem of ovarian endometrioma recurrence in the postoperative period. The data were analyzed based on foreign and domestic sources e-Library, Springer Nature, Wiley Journals, PubMed for 2016–2023 using the following keywords: «endometrioma», «risk factors», «recurrence», «prediction», «biomarkers». In the process of literature review, a significant relationship between infertility and ovarian endometriosis has been established, but all mechanisms in the occurrence of infertility in ovarian endometriomas remain incompletely understood. Noninvasive markers involved in the pathogenesis of the disease - apoptosis, angiogenesis, adhesion, as well as the possibilities of the diagnostic model of noninvasive diagnosis of endometriomas in the postoperative period are described in detail. The data on the effectiveness of drug therapy, as a way of preventing postoperative recurrence of the disease are highlighted and summarized.