Transcriptomic signatures in peripheral CD4+T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation
Specific pathways and marker genes in the peripheral CD4<sup>+</sup>T-cells may predetermine melanoma staging and immunotherapy resistance.
Authors
- Themis Alissafi (ORCID: https://orcid.org/0000-0002-4002-6008)
- Dimitrios C. Ziogas (ORCID: https://orcid.org/0000-0003-2620-4004)
- Matthieu D. Lavigne (ORCID: https://orcid.org/0000-0003-1543-8745)
- John M. Kirkwood
- Eleni Palli (ORCID: https://orcid.org/0000-0003-3081-6636)
- Amalia Anastasopoulou (ORCID: https://orcid.org/0000-0002-2147-7583)
- Helen J Gogas (ORCID: https://orcid.org/0000-0002-0451-2885)
- G. Lyrarakis
- Panagiotis Verginis
Institutions
- University of Crete (GR)
- University of Pittsburgh (US)
- National and Kapodistrian University of Athens (GR)
- Foundation for Research and Technology Hellas (GR)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-03-28
- DOI
- https://doi.org/10.3389/fimmu.2025.1529707
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00