DNA Damage Response and Repair Genes and Anthracycline-Induced Cardiomyopathy in Childhood Cancer Survivors: A Report From the Children’s Oncology Group and the Childhood Cancer Survivor Study
These findings provide evidence for the role of DDR genes and pathways in anthracycline-induced cardiomyopathy and provide a framework for targeted therapeutic interventions.
Authors
- Liting Zhou (ORCID: https://orcid.org/0009-0005-9995-6348)
- Eric Jessen Chow (ORCID: https://orcid.org/0000-0001-7712-961X)
- Yutaka Yasui (ORCID: https://orcid.org/0000-0002-7717-8638)
- Lindsey Hageman (ORCID: https://orcid.org/0009-0009-2396-5634)
- Changde Cheng (ORCID: https://orcid.org/0000-0002-2458-2522)
- Noha Sharafeldin (ORCID: https://orcid.org/0000-0001-8835-8899)
- Patrick J. Trainor (ORCID: https://orcid.org/0000-0002-3012-9716)
- Yadav Sapkota (ORCID: https://orcid.org/0000-0001-5943-9454)
- Romina B. Cejas (ORCID: https://orcid.org/0000-0002-5484-4722)
- Saro H. Armenian (ORCID: https://orcid.org/0000-0003-2604-8603)
- Smita Bhatia (ORCID: https://orcid.org/0000-0002-7755-5683)
- Jill P. Ginsberg (ORCID: https://orcid.org/0000-0001-7412-2017)
- Gregory T. Armstrong (ORCID: https://orcid.org/0000-0001-8722-4207)
- Wendy Landier (ORCID: https://orcid.org/0000-0003-3319-5652)
- Purnima Singh (ORCID: https://orcid.org/0000-0002-4968-7398)
- Joseph P. Neglia (ORCID: https://orcid.org/0000-0002-5525-0598)
- Douglas S. Hawkins (ORCID: https://orcid.org/0000-0003-3602-1375)
- Melissa M. Hudson (ORCID: https://orcid.org/0000-0001-6984-2407)
- Paul W. Burridge (ORCID: https://orcid.org/0000-0001-9616-0006)
- Fan Wang (ORCID: https://orcid.org/0000-0001-9806-5037)
- Xuexia Wang (ORCID: https://orcid.org/0000-0002-0613-2608)
Institutions
- Northwestern University (US)
- University of Minnesota (US)
- St. Jude Children's Research Hospital (US)
- Children's Hospital of Philadelphia (US)
- Florida International University (US)
- University of Alabama at Birmingham (US)
- Fred Hutch Cancer Center (US)
- Northwestern University (PH)
- Seattle Children's Hospital (US)
- City of Hope (US)
- Northwestern Medicine (US)
- L-3 Communications (United States) (US)
Publication Details
- Journal
- Circulation Genomic and Precision Medicine
- Published
- 2025-03-28
- DOI
- https://doi.org/10.1161/circgen.124.004813
- Citations
- 2
- Primary Topic
- Chemotherapy-induced cardiotoxicity and mitigation
- Type
- article
- Field-Weighted Citation Impact
- 2.78