Chemotherapy-Induced Neutropenic Enterocolitis in Acute Myeloid Leukaemia Patient: A Case Report

This case report details a 53-year-old woman with newly diagnosed acute myelogenous leukaemia (AML) who developed neutropenic enterocolitis (typhlitis) following induction chemotherapy.Initially presenting with mild respiratory symptoms and blood abnormalities, her condition worsened after chemotherapy, leading to severe gastrointestinal issues and pancytopenia.Diagnostic imaging and blood cultures confirmed neutropenic enterocolitis caused by Escherichia coli.The patient was successfully treated with broad-spectrum antibiotics, G-CSF, blood transfusions, and supportive care, resulting in a full recovery.This case highlights the importance of early diagnosis and prompt treatment of neutropenic enterocolitis in AML patients undergoing chemotherapy to improve outcomes and reduce mortality.

Publication Details

Journal
Texila international journal of public health
Published
2025-03-28
DOI
https://doi.org/10.21522/tijph.2013.13.01.art068
Primary Topic
Neutropenia and Cancer Infections
Type
article
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article

Chemotherapy-Induced Neutropenic Enterocolitis in Acute Myeloid Leukaemia Patient: A Case Report

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Texila international journal of public health
Neutropenia and Cancer Infections
article

Chemotherapy-Induced Neutropenic Enterocolitis in Acute Myeloid Leukaemia Patient: A Case Report

article en

Abstract

This case report details a 53-year-old woman with newly diagnosed acute myelogenous leukaemia (AML) who developed neutropenic enterocolitis (typhlitis) following induction chemotherapy.Initially presenting with mild respiratory symptoms and blood abnormalities, her condition worsened after chemotherapy, leading to severe gastrointestinal issues and pancytopenia.Diagnostic imaging and blood cultures confirmed neutropenic enterocolitis caused by Escherichia coli.The patient was successfully treated with broad-spectrum antibiotics, G-CSF, blood transfusions, and supportive care, resulting in a full recovery.This case highlights the importance of early diagnosis and prompt treatment of neutropenic enterocolitis in AML patients undergoing chemotherapy to improve outcomes and reduce mortality.

Texila international journal of public healthVol. 13(01)
Good health and well-being
Openalex Percentile: Top 91%
Neutropenia and Cancer Infections
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