Comparison of the Effectiveness and Safety of 5% Cysteamine and 2% Kojic Acid Creams in the Treatment of Melasma in Indian Adult Females

Five percent cysteamine cream demonstrated comparable effectiveness to 2% kojic acid cream in melasma patients, with the cysteamine group showing a numerical superiority in mMASI scores and Mexameter readings. Both treatments were well tolerated with no adverse effects. Therefore, 5% cysteamine cream is a valuable addition to the medical management of melasma.

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Publication Details

Journal
Cureus
Published
2025-03-28
DOI
https://doi.org/10.7759/cureus.81330
Citations
1
Primary Topic
Dermatologic Treatments and Research
Type
article
Field-Weighted Citation Impact
2.00
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article

Comparison of the Effectiveness and Safety of 5% Cysteamine and 2% Kojic Acid Creams in the Treatment of Melasma in Indian Adult Females

Ashwin Balasubramanian, Dhiraj S. Dhoot, Hanmant Barkate, Saiprasad Patil et al.
1 citations
Cureus
Dermatologic Treatments and Research
2.00
article

Comparison of the Effectiveness and Safety of 5% Cysteamine and 2% Kojic Acid Creams in the Treatment of Melasma in Indian Adult Females

Ashwin Balasubramanian, Dhiraj S. Dhoot, Hanmant Barkate, Saiprasad Patil, Raji Patil
article en
1 citations

Abstract

Five percent cysteamine cream demonstrated comparable effectiveness to 2% kojic acid cream in melasma patients, with the cysteamine group showing a numerical superiority in mMASI scores and Mexameter readings. Both treatments were well tolerated with no adverse effects. Therefore, 5% cysteamine cream is a valuable addition to the medical management of melasma.

CureusVol. 17(3)
Glenmark Pharmaceuticals (India) (IN)
Zero hunger
Openalex Percentile: Top 16%
Dermatologic Treatments and Research
2.00
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