Rhomboid proteases: key players at the cell surface within haloarchaea
This work highlights the role of rhomboid proteases in regulating critical cell surface processes in <i>H. volcanii</i>, including biofilm formation, surface adhesion, and cell shape determination. The ability of rho1 and <i>rho2</i> to compensate for each other in certain functions while maintaining distinct roles underscores a complex regulatory interplay. Future research will focus on identifying natural substrates and elucidating the molecular mechanisms underlying rhomboid protease function in haloarchaea.
Authors
- Rosana E. De Castro (ORCID: https://orcid.org/0000-0001-8889-4245)
- Micaela Cerletti (ORCID: https://orcid.org/0000-0002-8874-2804)
- Mariana Inés Costa (ORCID: https://orcid.org/0000-0001-5680-8285)
- Roberto A. Paggi (ORCID: https://orcid.org/0000-0003-0059-9343)
- María Inés Giménez (ORCID: https://orcid.org/0000-0002-2188-4154)
- Lucas Leonel Latorre
- Sofia Denise Frecha
- Valeria Zoratti
Institutions
- Consejo Nacional de Investigaciones Científicas y Técnicas (AR)
- National University of Mar del Plata (AR)
Publication Details
- Journal
- Frontiers in Microbiology
- Published
- 2025-03-28
- DOI
- https://doi.org/10.3389/fmicb.2025.1547649
- Citations
- 1
- Primary Topic
- Barrier Structure and Function Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.84