Long-term outcomes of endoscopic resection and tailored adjuvant radiotherapy for sinonasal intestinal-type adenocarcinoma: a historical single-center cohort study in 200 patients
This extensive study focusing on sinonasal ITAC primarily managed through endoscopic resection and radiotherapy, demonstrates that T-classification and tumor differentiation are independent prognostic factors influencing survival. Furthermore, local recurrence, distant metastasis, and positive surgical margins negatively affect OS and DSS.
Authors
- Paul M. Clément (ORCID: https://orcid.org/0000-0001-7600-0806)
- Thomas Decramer (ORCID: https://orcid.org/0000-0002-2585-581X)
- Laura Van Gerven (ORCID: https://orcid.org/0000-0002-5325-7956)
- Esther Hauben (ORCID: https://orcid.org/0000-0001-8688-9231)
- Vincent Vander Poorten (ORCID: https://orcid.org/0000-0003-1341-829X)
- Quentin-Alexandre Parys (ORCID: https://orcid.org/0000-0001-6209-4266)
- Sandra Nuyts (ORCID: https://orcid.org/0000-0002-5540-4796)
- Robert Hermans (ORCID: https://orcid.org/0000-0002-9935-5543)
- J. van Loon (ORCID: https://orcid.org/0000-0002-4684-0051)
- Mark Jorissen
- Matthias De Witte
Institutions
- KU Leuven (BE)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-03-28
- DOI
- https://doi.org/10.3389/fonc.2025.1522113
- Primary Topic
- Head and Neck Surgical Oncology
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Fonds Wetenschappelijk Onderzoek