Clonal Analysis of Peripheral Blood T Cells in patients with Hashimoto's Thyroiditis at Different Stages using TCR Sequencing

TCR sequencing highlights distinct clonal T cell expansions and shifts in VJ gene usage in HT patients, providing insights into the immune mechanisms driving disease progression.

Authors

Yufeng Liu (ORCID: https://orcid.org/0000-0001-6167-9852)
Yang Zhao (ORCID: https://orcid.org/0000-0002-3306-9835)
Qi Zhang (ORCID: https://orcid.org/0000-0001-7062-1126)
Huachao Zhu (ORCID: https://orcid.org/0000-0003-0941-2418)

Institutions

First Affiliated Hospital of Xi'an Jiaotong University (CN)

Publication Details

Journal: Immunobiology
Published: 2025-03-28
DOI: https://doi.org/10.1016/j.imbio.2025.152890
Primary Topic: T-cell and B-cell Immunology
Type: article
Field-Weighted Citation Impact: 0.00

Funders

Shanxi Provincial Key Research and Development Project
Key Research and Development Projects of Shaanxi Province

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article

Clonal Analysis of Peripheral Blood T Cells in patients with Hashimoto's Thyroiditis at Different Stages using TCR Sequencing

Yufeng Liu, Yang Zhao, Qi Zhang, Huachao Zhu

Mar 28, 2025

Immunobiology

T-cell and B-cell Immunology

article

Clonal Analysis of Peripheral Blood T Cells in patients with Hashimoto's Thyroiditis at Different Stages using TCR Sequencing

Yufeng Liu, Yang Zhao, Qi Zhang, Huachao Zhu

March 28, 2025article en

Abstract

TCR sequencing highlights distinct clonal T cell expansions and shifts in VJ gene usage in HT patients, providing insights into the immune mechanisms driving disease progression.

ImmunobiologyVol. 230(3)

First Affiliated Hospital of Xi'an Jiaotong University (CN)

Shanxi Provincial Key Research and Development Project, Key Research and Development Projects of Shaanxi Province

Zero hunger

Openalex Percentile: Top 94%

T-cell and B-cell Immunology

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Clonal Analysis of Peripheral Blood T Cells in patients with Hashimoto's Thyroiditis at Different Stages using TCR Sequencing — Yufeng Liu, Yang Zhao, et al. · Immunobiology (2025) | TGRS Research Map | TGRS