Improving image reconstruction to quantify dynamic whole-body PET/CT: Q.Clear versus OSEM
Q.Clear reconstruction of dynamic whole-body PET/CT data yields more precise <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mi>K</mml:mi> <mml:mi>i</mml:mi></mml:msub> </mml:math> values, especially for small values of <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:msub><mml:mi>K</mml:mi> <mml:mi>i</mml:mi></mml:msub> </mml:math> and smaller VOIs, compared to standard OSEM. This precision improvement shows Q.Clear's potential to better detect and characterize small lesion metabolic activity in oncology and allows for lower administered activity dosage.
Authors
- Walter H. Backes (ORCID: https://orcid.org/0000-0001-7905-0681)
- Tineke van de Weijer (ORCID: https://orcid.org/0000-0003-3485-7881)
- Roel Wierts (ORCID: https://orcid.org/0000-0002-9955-8754)
- Jeremy Basset‐Sagarminaga (ORCID: https://orcid.org/0009-0004-0685-6579)
- S Springer
- Vera B. Schrauwen‐Hinderling (ORCID: https://orcid.org/0000-0001-7795-584X)
Institutions
- Maastricht University Medical Centre (NL)
- Maastricht University (NL)
Publication Details
- Journal
- EJNMMI Physics
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1186/s40658-025-00736-5
- Citations
- 1
- Primary Topic
- Medical Imaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 1.36