New Insights Into the Correlation Between Necroptotic Activation and Neutrophil Infiltration in Pulpitis
Necroptosis occurs in pulpitis and correlates with immune cell infiltration. DPCs undergoing necroptosis can recruit neutrophils via the CXCL8/C3AR1 axis, exacerbating inflammation. This study offers new insights into the pathogenesis of pulpitis and potential therapeutic strategies.
Authors
- Louis T. Dang (ORCID: https://orcid.org/0000-0003-4853-4952)
- Zhao Chen (ORCID: https://orcid.org/0000-0001-8617-8560)
- Buling Wu (ORCID: https://orcid.org/0000-0002-9678-6962)
- Xiaolan Guo (ORCID: https://orcid.org/0000-0001-5113-0022)
- Peng Liu (ORCID: https://orcid.org/0000-0002-9639-6606)
- Xiaoxin Luke Chen (ORCID: https://orcid.org/0000-0002-4792-6156)
- Sitong Liu (ORCID: https://orcid.org/0000-0001-7355-1549)
- X.X. Ma
Institutions
- Nanfang Hospital (CN)
- Zhongshan People's Hospital (CN)
- Zhujiang Hospital (CN)
- Zhongshan Hospital (CN)
- Southern Medical University Shenzhen Hospital (CN)
- Southern Medical University (CN)
Publication Details
- Journal
- International Dental Journal
- Published
- 2025-03-26
- DOI
- https://doi.org/10.1016/j.identj.2025.02.016
- Citations
- 5
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 3.99