NSAID Induced Spontaneous Rectal Perforation

NSAID related spontaneous rectal perforation is a rare and severe condition with potentially life-threatening outcomes. We report a case of a 75-year-old woman with a mid-rectal perforation related to prolonged NSAID use. She presented with sudden rectal and lower abdominal pain. Imaging revealed a localised gas collection in the pre-sacral space without widespread peritonitis. Management included laparoscopic loop sigmoid colostomy and IV antibiotics. The patient recovered well and showed complete resolution at follow-up. This case highlights the importance of judicious use of NSAIDS in high-risk patients and underscores the need for individualised management strategies.

Authors

Publication Details

Journal
Frontiers in Medical Case Reports
Published
2025-01-01
DOI
https://doi.org/10.47746/fmcr.2025.6103
Citations
1
Primary Topic
Inflammatory mediators and NSAID effects
Type
article
Field-Weighted Citation Impact
1.39
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

NSAID Induced Spontaneous Rectal Perforation

Maheen Rana, Patricia Pantilie, Ben O’Sullivan, Robert Hannon
1 citations
Frontiers in Medical Case Reports
Inflammatory mediators and NSAID effects
1.39
article

NSAID Induced Spontaneous Rectal Perforation

Maheen Rana, Patricia Pantilie, Ben O’Sullivan, Robert Hannon
article en
1 citations

Abstract

NSAID related spontaneous rectal perforation is a rare and severe condition with potentially life-threatening outcomes. We report a case of a 75-year-old woman with a mid-rectal perforation related to prolonged NSAID use. She presented with sudden rectal and lower abdominal pain. Imaging revealed a localised gas collection in the pre-sacral space without widespread peritonitis. Management included laparoscopic loop sigmoid colostomy and IV antibiotics. The patient recovered well and showed complete resolution at follow-up. This case highlights the importance of judicious use of NSAIDS in high-risk patients and underscores the need for individualised management strategies.

Frontiers in Medical Case ReportsVol. 06(01)
Openalex Percentile: Top 22%
Inflammatory mediators and NSAID effects
1.39
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.