False hope of a single generalisable AI sepsis prediction model: bias and proposed mitigation strategies for improving performance based on a retrospective multisite cohort study

Implementing a single sepsis prediction model across all sites and care locations within multihospital systems may be unacceptable given large variances in NNE across multiple sites. Bias mitigation methods can identify models demonstrating improved performance across most sites in reducing alert burden but with no impact on the length of the prediction window.

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Publication Details

Journal
BMJ Quality & Safety
Published
2025-03-26
DOI
https://doi.org/10.1136/bmjqs-2024-018328
Citations
6
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
8.13
Controls
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article

False hope of a single generalisable AI sepsis prediction model: bias and proposed mitigation strategies for improving performance based on a retrospective multisite cohort study

Paul Lane, Anton H. van der Vegt, Ian A Scott, Vikrant R Kalke et al.
6 citations
BMJ Quality & Safety
Sepsis Diagnosis and Treatment
8.13
article

False hope of a single generalisable AI sepsis prediction model: bias and proposed mitigation strategies for improving performance based on a retrospective multisite cohort study

Paul Lane, Anton H. van der Vegt, Ian A Scott, Vikrant R Kalke, Rudolf J Schnetler
article en
6 citations

Abstract

Implementing a single sepsis prediction model across all sites and care locations within multihospital systems may be unacceptable given large variances in NNE across multiple sites. Bias mitigation methods can identify models demonstrating improved performance across most sites in reducing alert burden but with no impact on the length of the prediction window.

BMJ Quality & SafetyVol. 34(9)
The University of Queensland (AU), Townsville Hospital (AU), Queensland Government (AU), Metro South Health (AU), Prince Charles Hospital (AU)
Openalex Percentile: Top 2%
Sepsis Diagnosis and Treatment
8.13
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False hope of a single generalisable AI sepsis prediction model: bias and proposed mitigation strategies for improving performance based on a retrospective multisite cohort study — Paul Lane, Anton H. van der Vegt, et al. · BMJ Quality & Safety (2025) | TGRS Research Map | TGRS