Dosimetric analysis of beam number variations in IMRT for head-and-neck, breast, and pelvic cancers using Halcyon

This study investigated the dosimetric effects of varying beam numbers (9, 11, and 13) in intensity-modulated radiation therapy (IMRT) using the Halcyon linear accelerator at ShingMark University Hospital. IMRT plans for 27 patients with head-and-neck, breast, and pelvic cancers were evaluated according to the RTOG 0615 protocol, focusing on Planning Target Volume (PTV) dose coverage, uniformity, maximum and minimum doses, and Organ-at-Risk (OAR) dose constraints. For breast cancer, the 11-beam plan improved PTV coverage (V50Gy: 97.9 ± 0.5 %) and reduced maximum dose compared to 9- and 13-beam plans, while the 13-beam plan lowered heart mean dose by up to 10.5 % in left breast cases. In pelvic cases, the 13-beam plan enhanced OAR sparing, reducing bowel V35Gy by 10.5 % compared to the 9-beam plan, with minimal PTV coverage differences (<0.2 %). For head-and-neck cancer, the 13-beam plan improved PTV D95 % and spared critical structures like the brainstem, though it increased doses to the chiasm and cochlea. Treatment time and Monitor Units rose with more beams, particularly for head-and-neck and pelvic cases, but remained minimal for breast cases. These findings suggest tailoring beam numbers to cancer type and clinical priorities, balancing dosimetric benefits with treatment efficiency. • Evaluates the dosimetric impact of beam number variations in IMRT for multiple cancer sites. • Compares 9-, 11-, and 13-beam IMRT plans using the Halcyon linear accelerator. • Assesses dose conformity, homogeneity, and organ-at-risk sparing efficiency. • Provides clinical recommendations for optimizing IMRT planning strategies. • Contributes to personalized radiotherapy approaches in modern treatment settings.

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Publication Details

Journal
Radiation Physics and Chemistry
Published
2025-03-27
DOI
https://doi.org/10.1016/j.radphyschem.2025.112755
Citations
4
Primary Topic
Advanced Radiotherapy Techniques
Type
article
Field-Weighted Citation Impact
7.53

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article

Dosimetric analysis of beam number variations in IMRT for head-and-neck, breast, and pelvic cancers using Halcyon

Sitti Yani, Abdelmoneim Sulieman, Dương Thanh Tài, Nissren Tamam et al.
4 citations
Radiation Physics and Chemistry
Advanced Radiotherapy Techniques
7.53
article

Dosimetric analysis of beam number variations in IMRT for head-and-neck, breast, and pelvic cancers using Halcyon

Sitti Yani, Abdelmoneim Sulieman, Dương Thanh Tài, Nissren Tamam, James C. L. Chow, Peter Sandwall, Luong Tien Phat, Tran Trung Kien, Mai Thi Thao
article en
4 citations

Abstract

This study investigated the dosimetric effects of varying beam numbers (9, 11, and 13) in intensity-modulated radiation therapy (IMRT) using the Halcyon linear accelerator at ShingMark University Hospital. IMRT plans for 27 patients with head-and-neck, breast, and pelvic cancers were evaluated according to the RTOG 0615 protocol, focusing on Planning Target Volume (PTV) dose coverage, uniformity, maximum and minimum doses, and Organ-at-Risk (OAR) dose constraints. For breast cancer, the 11-beam plan improved PTV coverage (V50Gy: 97.9 ± 0.5 %) and reduced maximum dose compared to 9- and 13-beam plans, while the 13-beam plan lowered heart mean dose by up to 10.5 % in left breast cases. In pelvic cases, the 13-beam plan enhanced OAR sparing, reducing bowel V35Gy by 10.5 % compared to the 9-beam plan, with minimal PTV coverage differences (<0.2 %). For head-and-neck cancer, the 13-beam plan improved PTV D95 % and spared critical structures like the brainstem, though it increased doses to the chiasm and cochlea. Treatment time and Monitor Units rose with more beams, particularly for head-and-neck and pelvic cases, but remained minimal for breast cases. These findings suggest tailoring beam numbers to cancer type and clinical priorities, balancing dosimetric benefits with treatment efficiency. • Evaluates the dosimetric impact of beam number variations in IMRT for multiple cancer sites. • Compares 9-, 11-, and 13-beam IMRT plans using the Halcyon linear accelerator. • Assesses dose conformity, homogeneity, and organ-at-risk sparing efficiency. • Provides clinical recommendations for optimizing IMRT planning strategies. • Contributes to personalized radiotherapy approaches in modern treatment settings.

Radiation Physics and ChemistryVol. 236
Princess Nourah bint Abdulrahman University (SA), University Health Network (CA), King Saud bin Abdulaziz University for Health Sciences (SA), University of Toronto (CA), IPB University (ID), King Faisal Specialist Hospital & Research Centre (SA), Princess Margaret Cancer Centre (CA), Trường ĐH Nguyễn Tất Thành (VN), OhioHealth Mansfield Hospital (US), Hanoi Medical University Hospital (VN), Pham Ngoc Thach Hospital (VN)
Princess Nourah Bint Abdulrahman University
Good health and well-being
Openalex Percentile: Top 2%
Advanced Radiotherapy Techniques
7.53
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