Instant Intraoperative Histopathological Assessment of Fresh Parathyroid Tissue: Higher Harmonic Generation Microscopy as a Potential Alternative to Frozen Section
This proof-of-concept study demonstrates that HHGM could be a promising intraoperative diagnostic imaging modality, offering rapid imaging and detailed visualization capabilities. These features suggest that HHGM might potentially reduce surgery duration and decrease demand on pathology resources.
Authors
- E.J.M. Nieveen van Dijkum (ORCID: https://orcid.org/0000-0002-3029-6071)
- S. van Eeden
- Marie Louise Groot (ORCID: https://orcid.org/0000-0001-5360-6987)
- Sven van den Bosch (ORCID: https://orcid.org/0000-0002-0675-1847)
- P. M. Rodriguez Schaap (ORCID: https://orcid.org/0000-0002-7541-6516)
- Anton F. Engelsman (ORCID: https://orcid.org/0000-0003-4943-8882)
- S. Spies
Institutions
- Amsterdam University Medical Centers (NL)
- Vrije Universiteit Amsterdam (NL)
Publication Details
- Journal
- Head & Neck
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1002/hed.28146
- Primary Topic
- Thyroid and Parathyroid Surgery
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Nederlandse Organisatie voor Wetenschappelijk Onderzoek