AX-024 Inhibits Antigen-Specific T-Cell Response and Improves Intracerebral Hemorrhage Outcomes in Mice
AX-024 may represent a promising option for mitigating the detrimental effects of T cells entering the damaged brain without increasing bacterial loads in the lung in ICH. The potential of AX-024 as a potent immunosuppressive treatment for ICH is an exciting prospect that warrants further investigation.
Authors
- Chao Jiang (ORCID: https://orcid.org/0000-0001-5588-4294)
- Peiji Fu (ORCID: https://orcid.org/0000-0002-7517-8722)
- Jiewen Zhang (ORCID: https://orcid.org/0000-0001-6784-6658)
- Yan Zong (ORCID: https://orcid.org/0009-0004-6304-178X)
- Maosen Huang
- Li Zhu (ORCID: https://orcid.org/0000-0001-9430-5056)
- Chenhao Gao (ORCID: https://orcid.org/0000-0002-4342-1687)
- Yousef Rastegar‐Kashkooli (ORCID: https://orcid.org/0009-0007-5321-5653)
- Jian Wang (ORCID: https://orcid.org/0000-0003-2291-640X)
- Junmin Wang (ORCID: https://orcid.org/0000-0003-1823-5388)
- Shuai Chen (ORCID: https://orcid.org/0009-0001-6816-4293)
Institutions
- Zhengzhou University (CN)
- Fifth Affiliated Hospital of Zhengzhou University (CN)
- Henan Provincial People's Hospital (CN)
Publication Details
- Journal
- Stroke
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1161/strokeaha.124.048507
- Citations
- 6
- Primary Topic
- Neuroinflammation and Neurodegeneration Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 5.05