Pharmacokinetic simulations for remdesivir and its metabolites in healthy subjects and patients with renal impairment
A mathematical model has been developed that effectively captures the main pharmacokinetic features of RDV and its primary metabolites in both healthy subjects and patients with varying degrees of renal impairment.
Authors
- Seung Hee Jeong (ORCID: https://orcid.org/0000-0003-0001-3197)
- Harvey Ho (ORCID: https://orcid.org/0000-0002-4160-0737)
- Botao Jiang
- Shengjie Zhang (ORCID: https://orcid.org/0000-0001-9910-1976)
Institutions
- University of Auckland (NZ)
- Xianning Central Hospital (CN)
- Hubei University (CN)
Publication Details
- Journal
- Frontiers in Pharmacology
- Published
- 2025-03-27
- DOI
- https://doi.org/10.3389/fphar.2025.1488961
- Citations
- 1
- Primary Topic
- Antibiotics Pharmacokinetics and Efficacy
- Type
- article
- Field-Weighted Citation Impact
- 1.39