Adaptive radiotherapy for oropharyngeal cancer with daily adapt-to-shape workflow on 1.5 T MRI-linac: Preliminary outcomes and comparison with helical tomotherapy
Results of this analysis support the feasibility of an ATS MR-linac workflow for RCHT in OPSCC. Compared with tomotherapy, treatment with Unity® resulted in significantly lower rates of hospitalization and higher KPS three months after RT. Grade 2 xerostomia and dysgeusia rates were non-significantly lower in Unity group. Optimal results in terms of local control were reported for both techniques.
Authors
- Paolo Rondi (ORCID: https://orcid.org/0000-0003-4070-1277)
- Gianluca Cossali
- Michela Buglione (ORCID: https://orcid.org/0000-0002-5485-1260)
- Stefania Nici
- Davide Tomasini (ORCID: https://orcid.org/0000-0002-9007-522X)
- Marco Ravanelli (ORCID: https://orcid.org/0000-0002-4841-2771)
- Luigi Spiazzi (ORCID: https://orcid.org/0000-0001-8635-7411)
- Eneida Mataj (ORCID: https://orcid.org/0009-0002-5525-2945)
- Luca Triggiani (ORCID: https://orcid.org/0000-0003-0168-3432)
- Ludovica Pegurri
- Andrea Emanuele Guerini (ORCID: https://orcid.org/0000-0003-2094-1062)
- Stefano Maria Magrini (ORCID: https://orcid.org/0000-0002-4126-733X)
- Davide Farina (ORCID: https://orcid.org/0000-0003-4075-0001)
- Giorgio Facheris (ORCID: https://orcid.org/0000-0002-4555-1725)
- S. Riga (ORCID: https://orcid.org/0000-0002-1577-9542)
Institutions
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia (IT)
- University of Brescia (IT)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1016/j.ctro.2025.100950
- Citations
- 3
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.54
Funders
- Università degli Studi di Brescia