Comparison of pregnancy course and outcomes in patients with uterine fibroids following uterine artery embolisation or myomectomy

Aim. To determine the optimal surgical treatment for uter­ine fibroids in patients with unfulfilled reproductive through the analysis of pregnancy course and outcomes following uterine artery embolization (UAE) and myomectomy. Ma­terials and Methods. The study assessed pregnancy course and outcomes, as well as neonatal conditions, in 147 patients including those who: 1) underwent UAE; 2) underwent myo­mectomy; 3) had untreated uterine fibroids; 4) did not have uterine fibroids. Data collection was conducted retrospec­tively by reviewing medical records, including case histo­ries, pregnancy and delivery records, and newborn histories. Results. There have been significant differences in pregnan­cy complications and delivery methods among the women who received distinct surgical treatments for uterine fibroids (myomectomy vs. UAE). In the third trimester, placental ab­normalities were more frequent after UAE (12.5%) that af­ter myomectomy (2.9%) but cesarian delivery was performed twice as low (47.0% vs. 94.3, respectively). Subsequent preg­nancy risks were higher among the patients who had under­gone myomectomy, as 50% of them experienced fibroid re­currence during the pregnancy and there were scars on the uterus as a result of myomectomy and cesarean section. Con­clusion. No new fibroid nodules as well as growth or vas­cularization of existing fibroids were observed after UAE, suggesting that it can be considered as a preferred treatment option, particularly for women who have not yet completed their reproductive plans.

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Publication Details

Journal
Fundamental and Clinical Medicine
Published
2025-03-25
DOI
https://doi.org/10.23946/2500-0764-2025-10-1-47-55
Primary Topic
Uterine Myomas and Treatments
Type
article
Field-Weighted Citation Impact
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article

Comparison of pregnancy course and outcomes in patients with uterine fibroids following uterine artery embolisation or myomectomy

V. A. Gurjeva, Yu. A. Shadeeva, О. В. Ремнева, O. V. Kolyado
Fundamental and Clinical Medicine
Uterine Myomas and Treatments
article

Comparison of pregnancy course and outcomes in patients with uterine fibroids following uterine artery embolisation or myomectomy

V. A. Gurjeva, Yu. A. Shadeeva, О. В. Ремнева, O. V. Kolyado
article en

Abstract

Aim. To determine the optimal surgical treatment for uter­ine fibroids in patients with unfulfilled reproductive through the analysis of pregnancy course and outcomes following uterine artery embolization (UAE) and myomectomy. Ma­terials and Methods. The study assessed pregnancy course and outcomes, as well as neonatal conditions, in 147 patients including those who: 1) underwent UAE; 2) underwent myo­mectomy; 3) had untreated uterine fibroids; 4) did not have uterine fibroids. Data collection was conducted retrospec­tively by reviewing medical records, including case histo­ries, pregnancy and delivery records, and newborn histories. Results. There have been significant differences in pregnan­cy complications and delivery methods among the women who received distinct surgical treatments for uterine fibroids (myomectomy vs. UAE). In the third trimester, placental ab­normalities were more frequent after UAE (12.5%) that af­ter myomectomy (2.9%) but cesarian delivery was performed twice as low (47.0% vs. 94.3, respectively). Subsequent preg­nancy risks were higher among the patients who had under­gone myomectomy, as 50% of them experienced fibroid re­currence during the pregnancy and there were scars on the uterus as a result of myomectomy and cesarean section. Con­clusion. No new fibroid nodules as well as growth or vas­cularization of existing fibroids were observed after UAE, suggesting that it can be considered as a preferred treatment option, particularly for women who have not yet completed their reproductive plans.

Fundamental and Clinical MedicineVol. 10(1)
Altai State Medical University (RU)
Openalex Percentile: Top 92%
Uterine Myomas and Treatments
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