Andexanet alfa for reversal of intracerebral haemorrhage resulting in ST-segment myocardial infarction: a case report

This case emphasizes the need for individualized clinical assessment and collaboration with an interdisciplinary team regarding the use of andexanet alfa, as well as strategies to ensure thrombotic risk is effectively minimized. Current European Society of Cardiology Guidelines do not have recommendations for the use of andexanet alfa for the reversal of anticoagulation due to its uncertain risk profile. This case emphasizes the increased risk of thrombotic complications associated with andexanet alfa and highlights the importance of the continued need to research its use, which may help elucidate or revise current guidelines.

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Publication Details

Journal
European Heart Journal - Case Reports
Published
2025-03-23
DOI
https://doi.org/10.1093/ehjcr/ytaf136
Citations
2
Primary Topic
Atrial Fibrillation Management and Outcomes
Type
article
Field-Weighted Citation Impact
2.78
Controls
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article

Andexanet alfa for reversal of intracerebral haemorrhage resulting in ST-segment myocardial infarction: a case report

Nathan DeRon, Shaheen Mehrara, Ravi Patel
2 citations
European Heart Journal - Case Reports
Atrial Fibrillation Management and Outcomes
2.78
article

Andexanet alfa for reversal of intracerebral haemorrhage resulting in ST-segment myocardial infarction: a case report

Nathan DeRon, Shaheen Mehrara, Ravi Patel
article en
2 citations

Abstract

This case emphasizes the need for individualized clinical assessment and collaboration with an interdisciplinary team regarding the use of andexanet alfa, as well as strategies to ensure thrombotic risk is effectively minimized. Current European Society of Cardiology Guidelines do not have recommendations for the use of andexanet alfa for the reversal of anticoagulation due to its uncertain risk profile. This case emphasizes the increased risk of thrombotic complications associated with andexanet alfa and highlights the importance of the continued need to research its use, which may help elucidate or revise current guidelines.

European Heart Journal - Case ReportsVol. 9(4)
Methodist Dallas Medical Center (US)
Openalex Percentile: Top 11%
Atrial Fibrillation Management and Outcomes
2.78
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