Zerlasiran for the Treatment of Atherosclerotic Cardiovascular Disease

To the Editor A recent article1 reported that zerlasiran was well tolerated, with a time-averaged percent change in lipoprotein(a) concentration of more than 80% from baseline to 36 weeks in patients with atherosclerotic cardiovascular disease. However, we have some concerns about this study.

Authors

Institutions

Publication Details

Journal
JAMA
Published
2025-03-27
DOI
https://doi.org/10.1001/jama.2025.0031
Citations
1
Primary Topic
Hormonal Regulation and Hypertension
Type
article
Field-Weighted Citation Impact
1.29
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Zerlasiran for the Treatment of Atherosclerotic Cardiovascular Disease

Jiahao Meng, Shuguang Gao, Yumei Wu
1 citations
JAMA
Hormonal Regulation and Hypertension
1.29
article

Zerlasiran for the Treatment of Atherosclerotic Cardiovascular Disease

Jiahao Meng, Shuguang Gao, Yumei Wu
article en
1 citations

Abstract

To the Editor A recent article1 reported that zerlasiran was well tolerated, with a time-averaged percent change in lipoprotein(a) concentration of more than 80% from baseline to 36 weeks in patients with atherosclerotic cardiovascular disease. However, we have some concerns about this study.

JAMAVol. 333(16)
Central South University (CN), Xiangya Hospital Central South University (CN)
Good health and well-being
Openalex Percentile: Top 21%
Hormonal Regulation and Hypertension
1.29
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.