Urinary total 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanonol is positively associated with tooth loss
Our study revealed a positive relationship between urinary TNNAL and tooth loss, and further demonstrated the mediating role of RDW and MHR between the TNNAL and the number of missing teeth in the whole popualtion. These findings will provide new theoretical insights for policy formulation and clinical therapeutic for the target prevention and intervention of related diseases.
Authors
- Rui Zou (ORCID: https://orcid.org/0000-0003-1214-9606)
- Shaojie Dong (ORCID: https://orcid.org/0000-0001-6021-3620)
- Zhenya Ding (ORCID: https://orcid.org/0000-0002-5388-8803)
- Yuwei Zhang (ORCID: https://orcid.org/0000-0003-2909-3397)
- Yifei Zhang
- Zhu Hu (ORCID: https://orcid.org/0000-0002-4669-5245)
- Xuefei Sun
- Lin Niu (ORCID: https://orcid.org/0000-0001-5093-0255)
- Jingning Gou
- Yue Jia (ORCID: https://orcid.org/0009-0003-5434-7333)
- Changjie Sun
- Luming Wang (ORCID: https://orcid.org/0000-0002-7541-4545)
Institutions
- Hong Kong Polytechnic University (HK)
- Chinese University of Hong Kong (HK)
- Xi'an Jiaotong University (CN)
Publication Details
- Journal
- BMC Public Health
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1186/s12889-025-22173-w
- Primary Topic
- Oral microbiology and periodontitis research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Basic Research Program of Shaanxi Province