Assessment of skin fibrosis in a murine model of systemic sclerosis with multifunctional optical coherence tomography
Our results indicate that OCT and its extensions effectively analyze dermal fibrosis. OCE revealed increased stiffness in fibrotic skin, OCTA showed vessel dilation, and OCT noted morphological changes in fibrosis tissue.
Authors
- Harshdeep S. Chawla (ORCID: https://orcid.org/0009-0004-3222-8613)
- Pavel V. Nikitin (ORCID: https://orcid.org/0000-0003-3223-4584)
- Jessica Gutiérrez (ORCID: https://orcid.org/0000-0003-0024-0672)
- Manmohan Singh (ORCID: https://orcid.org/0000-0002-8396-5451)
- Shervin Assassi (ORCID: https://orcid.org/0000-0002-8059-9978)
- Chandra Mohan (ORCID: https://orcid.org/0000-0001-7896-5740)
- Minghua Wu (ORCID: https://orcid.org/0000-0002-0388-2032)
- Kirill V. Larin (ORCID: https://orcid.org/0000-0002-5532-5027)
- Salavat R. Aglyamov (ORCID: https://orcid.org/0000-0001-9530-1225)
- Yanping Chen (ORCID: https://orcid.org/0000-0002-0000-2079)
Institutions
- Baylor College of Medicine (US)
- University of Houston (US)
- The University of Texas Health Science Center at Houston (US)
Publication Details
- Journal
- Journal of Biomedical Optics
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1117/1.jbo.30.3.036007
- Citations
- 2
- Primary Topic
- Systemic Sclerosis and Related Diseases
- Type
- article
- Field-Weighted Citation Impact
- 2.94