Incidence and Factors Associated With Spontaneous Regression in Head and Neck Lymphatic Malformations
In this cohort study, HNLMs that were macrocystic, of limited extent, and/or in the neck were more likely to completely spontaneously regress. A 1-year observation period for asymptomatic HNLM, particularly when favorable features are present, should be considered, as nonintervention may be curative. Future studies will examine interaction among these factors. This work contributes to a deeper understanding of HNLM natural history that can directly inform clinical decision-making, decrease treatment risk, and optimize patient outcomes.
Authors
- Tara Lynn Wenger (ORCID: https://orcid.org/0000-0002-1703-1546)
- Bonnie W. Ramsey (ORCID: https://orcid.org/0000-0001-7116-5281)
- Jonathan A. Perkins (ORCID: https://orcid.org/0000-0003-0181-3997)
- Xing Wang (ORCID: https://orcid.org/0000-0002-5950-4591)
- Juliana Bonilla‐Velez (ORCID: https://orcid.org/0000-0002-7174-7609)
- Larry G. Kessler (ORCID: https://orcid.org/0000-0002-8024-5424)
- Carrie L. Heike (ORCID: https://orcid.org/0000-0003-2178-7730)
Institutions
- Seattle Children's Hospital (US)
- University of Washington (US)
Publication Details
- Journal
- JAMA Otolaryngology–Head & Neck Surgery
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1001/jamaoto.2025.0104
- Citations
- 1
- Primary Topic
- Vascular Malformations and Hemangiomas
- Type
- article
- Field-Weighted Citation Impact
- 2.01