Idiopathic epilepsy in dogs is associated with dysbiotic faecal microbiota
Idiopathic epileptic dogs exhibit dysbiosis, with reduced bacterial diversity, loss of beneficial genera, and overgrowth of opportunistic pathogens. These alterations in microbiota diversity and composition may contribute to epilepsy via the gut-brain axis, highlighting the need for further research to explore dietary or probiotic interventions targeting gut microbiota modulation as adjunctive therapies for managing epilepsy in dogs.
Authors
- Andrea Zatelli (ORCID: https://orcid.org/0000-0003-0001-7710)
- Viviana Domenica Tarallo
- Floriana Gernone (ORCID: https://orcid.org/0000-0002-6256-3832)
- Angelica Bianco (ORCID: https://orcid.org/0000-0002-6156-4657)
- Mattia Pirolo (ORCID: https://orcid.org/0000-0002-9814-1500)
- Stefano Castellana (ORCID: https://orcid.org/0000-0001-8688-9530)
- Laura Del Sambro (ORCID: https://orcid.org/0000-0002-2729-9933)
- Luca Guardabassi (ORCID: https://orcid.org/0000-0002-2389-5084)
- Marco Silvestrino (ORCID: https://orcid.org/0000-0001-9139-8015)
Institutions
- University of Copenhagen (DK)
- Istituto Zooprofilattico Sperimentale della Puglia e della Basilicata (IT)
- University of Bari Aldo Moro (IT)
Publication Details
- Journal
- Animal Microbiome
- Published
- 2025-03-27
- DOI
- https://doi.org/10.1186/s42523-025-00397-w
- Citations
- 5
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- European Commission
- European Social Fund