Neuroendocrine Deficits and Weight Development Before and After Proton Therapy in Children With Craniopharyngioma

Panhypopituitarism is frequently observed in paediatric patients with craniopharyngioma prior to PBT. The potential benefits of early PBT on endocrine outcomes require further investigation through longer FU periods. The greatest increase in weight occurred before radiotherapy. Endocrine deficiencies and weight gain are multifactorial and require close monitoring.

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Publication Details

Journal
Clinical Oncology
Published
2025-03-27
DOI
https://doi.org/10.1016/j.clon.2025.103837
Citations
2
Primary Topic
Pituitary Gland Disorders and Treatments
Type
article
Field-Weighted Citation Impact
2.59

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article

Neuroendocrine Deficits and Weight Development Before and After Proton Therapy in Children With Craniopharyngioma

Julia Beckhaus, Hermann L. Müller, Brigitte Bison, Diana Khalil et al.
2 citations
Clinical Oncology
Pituitary Gland Disorders and Treatments
2.59
article

Neuroendocrine Deficits and Weight Development Before and After Proton Therapy in Children With Craniopharyngioma

Julia Beckhaus, Hermann L. Müller, Brigitte Bison, Diana Khalil, Filiz Şen, Martin Bischoff, Cordula Kiewert, Benjamin Koska, Beate Timmermann, Carsten Friedrich, S. Frisch, R.-D. Kortmann
article en
2 citations

Abstract

Panhypopituitarism is frequently observed in paediatric patients with craniopharyngioma prior to PBT. The potential benefits of early PBT on endocrine outcomes require further investigation through longer FU periods. The greatest increase in weight occurred before radiotherapy. Endocrine deficiencies and weight gain are multifactorial and require close monitoring.

Clinical OncologyVol. 42
University of Augsburg (DE), Klinikum Oldenburg (DE), Essen University Hospital (DE), West German Heart and Vascular Center Essen (DE), University of Duisburg-Essen (DE), Leipzig University (DE)
Universität Duisburg-Essen
Openalex Percentile: Top 11%
Pituitary Gland Disorders and Treatments
2.59
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Neuroendocrine Deficits and Weight Development Before and After Proton Therapy in Children With Craniopharyngioma — Julia Beckhaus, Hermann L. Müller, et al. · Clinical Oncology (2025) | TGRS Research Map | TGRS